Learning Objectives:

1. Explain the basis of Nernst potential and its importance in generation of resting membrane potential

2. Comprehend different mechanisms responsible for the genesis of membrane potential

3. Use the Goldman equation to explain how the relative permeability of the ions creates a resting membrane potential

Learning Objectives:

1. Define action potential

2. Illustrate different phases of action potential and explain ionic & electrical changes occurring during each phase of action potential

3. Differentiate between myelinated and nonmyelinated nerve fibers based on their structure and characteristics

4. Describe the conduction of action potential in unmyelinated and myelinated neurons

5. Explain the concept of saltatory conduction

6. Differentiate between action potential and local potential

Learning Objectives:

1.Explain the concept of all or nothing principle in propagation of an action potential

2.Differentiate between absolute and relative refractory periods

3.Explain the effect of hypocalcemia on permeability of sodium channels

4.Distinguish the effects of hyperkalemia, hypercalcemia, and hypoxia on the resting membrane potential & action potential