Strengthen your understanding of core physiology with this focused series on homeostasis and cell function from Medicose Academics. This page covers essential concepts from cellular structure and membrane transport to genetic control and temperature regulation, based on Guyton and Hall Textbook of Medical Physiology. It is designed for medical students and candidates preparing for USMLE, PLAB, FCPS, and NEET PG. You will learn how cells maintain internal balance, how membranes regulate transport, and how physiological control systems operate in health and disease, helping you solve exam questions and apply concepts in clinical practice.
Content List:
Functional Organization of Human Body
Homeostatic control of the Internal body env
Cell/Plasma Membrane of cell: applied/clinical Physio
Genetic Control of Cellular Functions
Transport across of the Cell Membrane
Functional Organization of the Human Body and Control of the “Internal Environment”
Guyton & Hall, Ed 14, CH 1
Define Physiology.
Describe the functional organisation of the human body from cell to system.
• Define Homeostasis.
• Explain control system of body by giving examples.
• Differentiate between Extracellular and Intracellular Fluids.
• Explain the positive and negative feedback mechanisms with examples.
• Explain the significance of feed forward, adaptive control, and delayed negative feedback mechanisms.
The Cell and Its Functions
Guyton & Hall, ed 15, CH 2
• Describe the structure and composition of a human cell membrane.
• Describe how the distribution of phospholipids and proteins influences membrane permeability of ions, hydrophilic and hydrophobic compounds.
• Enlist the various functions of integral and peripheral proteins in the cell membrane.
• Differentiate membranous organelles from nonmembranous organelles.
• Describe the structure and function of nucleus, nuclear membrane, chromatin, chromosomes, nucleoplasm, and nucleolus.
• Compare the structure and function of smooth endoplasmic reticulum and rough endoplasmic reticulum.
• Explain the importance of Golgi apparatus in packaging and storage of newly formed proteins.
• Describe the structure and functions of vaults.
• Describe the synthesis, types, and functions of ribosomes.
• Summarize the structure and functions of secretory vesicles.
• Discuss the physiological anatomy of mitochondria and its role in energy synthesis.
• Compare and contrast the functions of lysosomes and peroxisomes.
• Describe the structure and function of the cell cytoskeleton
• microtubules
• microfilaments
• intermediate filaments.
• Describe the mechanism of movements of cells
• amoeboid
• ciliary
• flagellar movements
• Enumerate the different types of cells junctions
• Differentiate cells junctions based on structure & function
Genetic Control of Protein Synthesis, Cell Function, and Cell Reproduction
Guyton & Hall, ed 15, Ch3
Describe the structure of DNA
Recognise the different types of RNA
Briefly describe the steps of transcription to elucidate the functions of different types of RNA
Briefly describe the process of translation
Discuss the mechanisms of genetic control of cell functions
Describe the cell cycle
Briefly describe the process of DNA replication
Describe the control of cell reproduction by telomeres and telomerase
Compare and contrast apoptosis and necrosis
Explain the pathophysiology of cancer and ageing
Transport of Substances Through Cell Membranes
Guyton & Hall, ed 15, Ch3
• Describe different types of transport across the cell membrane.
• Differentiate between active and passive transport.
• Enlist the characteristics of various cell membrane transporters.
• Describe osmosis and its characteristics.
• Differentiate between osmolarity and tonicity.
• Describe the relation between osmolarity and osmotic pressure.
• Enumerate characteristics of different types of vesicular transport across the cellular membrane.
Body Temperature Regulation & Fever
Guyton & Hall, ed 15, Ch74
• Define normal body temperature.
• Describe the physiological mechanisms of heat loss and heat production in human body.
• Describe the physiological regulation of body temperature.
• Describe the abnormalities of body temperature regulation